Niacinamide melasma. Method: a literature review was performed based on a data search in Jul 15, 2022 · Niacinamide, or vitamin B3, is a water-soluble vitamin essential for maintaining healthy skin and can help reduce melasma symptoms. . This work showed that niacinamide 4% is an effective agent for the treatment of melasma, as assessed by objective methods and clinical evaluation. Topical niacinamide may be considered a beneficial and safe therapeutic choice for the management of melasma [22, 23, 24, 25]. Sunscreen was applied along the observation period. By inhibiting the transfer of melanosomes from melanocytes to keratinocytes, niacinamide effectively lightens melasma patches. Aug 20, 2022 · Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly to therapies, negatively affecting the quality of life of patients. Jul 11, 2022 · Melasma is known as the "mask of pregnancy" since hormonal changes caused by pregnancy, as well as hormonal medications such as birth control pills, are major triggers for excessive skin pigment production in melasma. Twenty-seven melasma patients were randomized to receive for eight weeks 4% niacinamide cream on one side of the face, and 4% HQ cream on the other. 4 days ago · A cult-favorite niacinamide serum Board-certified dermatologist Blair Murphy-Rose named niacinamide as an ingredient that can treat and prevent melasma by interfering with melanin synthesis in the skin. Objective: to Abstract Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly to therapies, negatively affecting the quality of life of patients. Sun exposure is another important contributor to melasma. One significant way is through its ability to reduce melanin production, the pigment responsible for skin colour. Objective: to know and analyze the scientific evidence related to the treatment of patients with facial melasma treated with niacinamide. Apr 15, 2025 · The best products for melasma use science-backed ingredients like tranexamic acid and niacinamide to offset the brown patches associated with the skin condition. Niacinamide is the biologically active form of niacin (vitamin B3) and reduces skin pigmentation by decreasing the accumulation of melanin [20, 21]. Nov 8, 2024 · The Mechanism of Niacinamide in Treating Melasma Niacinamide acts on multiple fronts to address melasma. Sep 5, 2025 · Discover how niacinamide helps reduce melasma and hyperpigmentation, even on darker skin tones. Our results indicate that 4% niacinamide was effective in approximate 40% of patients, showing outstanding clinical results. Learn the best routine, product tips, and complementary ingredients for brighter, even-toned skin. Can melasma be prevented? Jul 21, 2011 · The mechanism of action of niacinamide in melasma could be through the reduction of melanosomes transfer [3], photoprotection actions [4], its anti-inflammatory properties [5], and a direct or related antiaging effects such as reduction of solar elastosis [9]. See full list on dermamade. It's also an antioxidant that she said can prevent free radical environmental damage to the skin. The exact mechanism by which niacinamide reduces melasma symptoms has yet to be fully understood, but several proposed theories exist. com 2 days ago · The formula also contains skin-healthy niacinamide to help inhibit the transfer of pigment to skin cells and offer anti-inflammatory benefits, which is crucial for managing melasma. zeh zsyuwi czvbc rxv hrbxy xrea qlp hcoyuu piklbk phy