Centromeres definition. Centromeres help in the proper alignment and segregation of the chromosomes during the process of cell division in eukaryotic cells. Centromere definition: a specialized structure on the chromosome, appearing during cell division as the constricted central region where the two chromatids are held together and form an X shape. During cell division, the kinetochore forms at the centromere and is responsible for pulling apart sister chromatids to opposite poles of the cell. Centromeres were first described by Walther Flemming in 1882 as the primary constrictions on chromosomes to which fibers emanating from the spindle made physical connections. They are essential for the proper segregation of sister chromatids into daughter cells, ensuring genetic stability. Specifically, it is the region where the cell’s spindle fibers attach. Explore what centromeres are, its structure, position on chromosomes, types, and essential roles during cell division. In simple terms, centromeres are like the glue that holds chromosomes together. Aug 3, 2023 · When a cell divides, the centromere, which resembles a constrictive area of a chromosome, is fundamental in assisting in the division of the DNA within the cell (mitosis and meiosis) during the metaphase stage. Centromeres play an important part in the production of a new cell. Centromere Centromere n. , plural: centromeres [ˈsɛntɹəˌmiɚ/] Definition: the region in a chromosome where kinetochore is located Centromeres are characterized by the presence of specific histone proteins that form a structure known as the centromeric chromatin. 3 days ago · The centromere appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (mitosis and meiosis). When the chromosomes are copied, these centromere serves as a binding site for the two replicated chromosomes, which are known as sister chromatids. centromere, structure in a chromosome that holds together the two chromatids (the daughter strands of a replicated chromosome). . See examples of CENTROMERE used in a sentence. The meaning of CENTROMERE is the point or region on a chromosome to which the spindle attaches during mitosis and meiosis. The centromere is the point of attachment of the kinetochore, a structure to which the microtubules of the mitotic spindle become anchored. The centromere structure can influence the behavior of chromosomes and is involved in processes like whole-genome sequencing Jun 20, 2016 · Centromeres are the key. Regarding mitotic chromosome structure, centromeres represent a constricted region of the chromosome (often referred to as the primary constriction) where two identical sister chromatids are most closely in contact. Jul 23, 2025 · Centromeres do a lot of important jobs, like keeping sister chromatids together, moving chromosomes, sticking to microtubules, forming heterochromatin, and controlling the mitotic checkpoint. Centromeres are specialized regions of chromosomes that play a critical role during cell division by serving as the attachment point for spindle fibers. By the early 1900s, centromeres had acquired a genetic definition: the sites on a chromosome responsible for its inheritance. ikeum brtm wdzaj vspv ftzfaod nsdy ofj hke gjk ednvyb